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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PBK All Species: 35.45
Human Site: S59 Identified Species: 60
UniProt: Q96KB5 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.23
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q96KB5 NP_060962.2 322 36085 S59 S P R G L S H S P W A V K K I
Chimpanzee Pan troglodytes XP_520045 322 36011 S59 S P R G L S H S P W A V K K I
Rhesus Macaque Macaca mulatta XP_001109768 323 36123 S59 S P R G L S H S P W A V K K I
Dog Lupus familis XP_534564 324 36430 S59 S P R G L S H S P W A V K K I
Cat Felis silvestris
Mouse Mus musculus Q9JJ78 330 36726 P59 P R G L S H S P W A V K K I S
Rat Rattus norvegicus NP_001073406 337 37551 S59 S P R G L S H S P W A V K K I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508951 321 35996 S59 S P K G L S Q S P W A V K K I
Chicken Gallus gallus XP_420011 322 35395 K59 R S P W A V K K I N S K C S K
Frog Xenopus laevis NP_001088960 325 36517 S60 S P K G L S H S P W A V K K I
Zebra Danio Brachydanio rerio Q6DHU8 339 37645 S62 R M G K Q T H S P W A I K K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_573239 398 44994 R62 R S P W A V K R I T Q N M R V
Honey Bee Apis mellifera XP_623765 343 38973 S59 P K V G F I R S P W A I K K R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798752 344 37735 S80 R P D G S G R S P W A V K K I
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001130276 278 30401 R24 Y K A V L D G R L V V I V K R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96.5 93.5 N.A. 85.4 86.3 N.A. 83.2 73.5 70.1 64 N.A. 35.9 41.4 N.A. 46.5
Protein Similarity: 100 99.6 98.7 96.9 N.A. 92.4 91.9 N.A. 89.7 85.4 85.2 77.2 N.A. 51.2 58.8 N.A. 63.9
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 86.6 0 93.3 53.3 N.A. 0 46.6 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 6.6 100 N.A. 93.3 6.6 100 66.6 N.A. 13.3 53.3 N.A. 66.6
Percent
Protein Identity: N.A. 26.7 N.A. N.A. N.A. N.A.
Protein Similarity: N.A. 45.6 N.A. N.A. N.A. N.A.
P-Site Identity: N.A. 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. 20 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 15 0 0 0 0 8 72 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 8 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 65 0 8 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 8 50 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 15 0 0 22 0 8 65 % I
% Lys: 0 15 15 8 0 0 15 8 0 0 0 15 79 79 8 % K
% Leu: 0 0 0 8 58 0 0 0 8 0 0 0 0 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % N
% Pro: 15 58 15 0 0 0 0 8 72 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 8 0 8 0 0 0 8 0 0 0 0 % Q
% Arg: 29 8 36 0 0 0 15 15 0 0 0 0 0 8 15 % R
% Ser: 50 15 0 0 15 50 8 72 0 0 8 0 0 8 8 % S
% Thr: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % T
% Val: 0 0 8 8 0 15 0 0 0 8 15 58 8 0 8 % V
% Trp: 0 0 0 15 0 0 0 0 8 72 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _